FNTB 抗体
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北京 101111
Quick Overview for FNTB 抗体 (ABIN317932)
抗原
See all FNTB 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- FTβ antibody detects endogenous levels of FTβ protein.(region surrounding Glu285)
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纯化方法
- Affinity chromatography
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FNTB (Farnesyltransferase subunit beta (FNTB))
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别名
- FNTB
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背景
- Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical α and β subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an α-β heterodimer. The β subunit binds the peptide substrate while the α subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate. The α subunit is shared with a second prenyl transferase, geranyl-geranyl transferase, that attaches 20 carbon geranylgeranyl to Ras related proteins that terminate in a Cys-A-A-Xaa recognition site in which Xaa is leucine.Synonyms: CAAX farnesyltransferase subunit beta, FTase-beta, Protein farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta
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分子量
- approx. 50 kDa
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基因ID
- 2342
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NCBI登录号
- NP_002019
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UniProt
- P49356
抗原
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