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FNTB 抗体

This 兔 多克隆 antibody specifically detects FNTB in WB. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN317932
发货至: 中国
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Quick Overview for FNTB 抗体 (ABIN317932)

抗原

See all FNTB 抗体
FNTB (Farnesyltransferase subunit beta (FNTB))

适用

  • 60
  • 31
  • 14
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 59
  • 1

克隆类型

  • 39
  • 21
多克隆

标记

  • 23
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
This FNTB antibody is un-conjugated

应用范围

  • 40
  • 23
  • 14
  • 13
  • 11
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 特异性

    FTβ antibody detects endogenous levels of FTβ protein.(region surrounding Glu285)

    纯化方法

    Affinity chromatography
  • 应用备注

    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FNTB (Farnesyltransferase subunit beta (FNTB))

    别名

    FNTB

    背景

    Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical α and β subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an α-β heterodimer. The β subunit binds the peptide substrate while the α subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate. The α subunit is shared with a second prenyl transferase, geranyl-geranyl transferase, that attaches 20 carbon geranylgeranyl to Ras related proteins that terminate in a Cys-A-A-Xaa recognition site in which Xaa is leucine.Synonyms: CAAX farnesyltransferase subunit beta, FTase-beta, Protein farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta

    分子量

    approx. 50 kDa

    基因ID

    2342

    NCBI登录号

    NP_002019

    UniProt

    P49356
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