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FNTB 抗体 (N-Term)

FNTB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4769-4770 unconjugated
产品编号 ABIN389047
发货至: 中国
  • 抗原 See all FNTB 抗体
    FNTB (Farnesyltransferase subunit beta (FNTB))
    抗原表位
    • 7
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-36, N-Term
    适用
    • 53
    • 23
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 52
    • 1
    克隆类型
    • 41
    • 12
    多克隆
    标记
    • 24
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This FNTB antibody is un-conjugated
    应用范围
    • 33
    • 25
    • 13
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B, Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This FNTB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human FNTB.
    克隆位点
    RB4769-4770
    亚型
    Ig Fraction
    Top Product
    Discover our top product FNTB Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    FNTB (Farnesyltransferase subunit beta (FNTB))
    别名
    FNTB (FNTB 产品)
    别名
    FPTB antibody, 2010013E13Rik antibody, AA409500 antibody, farnesyltransferase, CAAX box, beta antibody, FNTB antibody, Fntb antibody
    背景
    Eukaryotic cells contain 3 different types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in a variety of proteins. These posttranslational modifications provide a mechanism for membrane localization of proteins that lack a transmembrane domain. CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This enzyme has the ability to farnesylate peptides as short as 4 residues in length that conform to the CAAX consensus sequence. The gene for the beta subunit of CAAX farnesyltransferase (FNTB) has been pinpointed to 14q23-q24 by Southern blot hybridization and PCR analyses of panels of human/Chinese hamster somatic cell hybrid lines and by fluorescence chromosomal in situ hybridization.
    分子量
    48774
    基因ID
    2342
    NCBI登录号
    NP_002019
    UniProt
    P49356
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