KCNK1
适用: 小鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 488
应用备注
ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
KCNK1
(Potassium Channel Subfamily K Member 1 (KCNK1))
AI788889 antibody, TWIK-1 antibody, DPK antibody, HOHO antibody, K2P1 antibody, K2p1.1 antibody, KCNO1 antibody, TWIK1 antibody, Twik antibody, k2p1.1 antibody, twik-1 antibody, twik1 antibody, rabKCNK1 antibody, im:7150627 antibody, kcnk1 antibody, zgc:165664 antibody, potassium channel, subfamily K, member 1 antibody, potassium two pore domain channel subfamily K member 1 antibody, potassium channel, two pore domain subfamily K, member 1 L homeolog antibody, potassium channel, subfamily K, member 1a antibody, Kcnk1 antibody, KCNK1 antibody, kcnk1.L antibody, kcnk1a antibody
背景
K+ channels are divided into three subclasses, reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions, and include TASK, TREK, TRAAK and TWIK. TWIK-1 mRNA is expressed abundantly in brain and at lower levels in lung, kidney and skeletal muscle. The molecular weight of TWIK-1 in mouse brain is 40 kDa under reducing conditions. TWIK-2 shares low sequence homology with other mammalian family group members, and only 34 % homology with TWIK-1. Human TWIK-2 is expressed in pancreas, placenta and heart, while mouse TWIK-2 is expressed in liver. TWIK-2 is inhibited by intracellular, but not extracellular, acidification.Synonyms: HOHO1, Inward rectifying potassium channel protein TWIK-1, KCNK1, KCNO1, Potassium channel KCNO1, Potassium channel subfamily K member 1, TWIK1