KCNK1 抗体
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北京 101111
Quick Overview for KCNK1 抗体 (ABIN317929)
抗原
See all KCNK1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of TWIK-1 protein.(region surrounding Val322)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KCNK1 (Potassium Channel Subfamily K Member 1 (KCNK1))
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别名
- KCNK1
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背景
- K+ channels are divided into three subclasses, reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions, and include TASK, TREK, TRAAK and TWIK. TWIK-1 mRNA is expressed abundantly in brain and at lower levels in lung, kidney and skeletal muscle. The molecular weight of TWIK-1 in mouse brain is 40 kDa under reducing conditions. TWIK-2 shares low sequence homology with other mammalian family group members, and only 34 % homology with TWIK-1. Human TWIK-2 is expressed in pancreas, placenta and heart, while mouse TWIK-2 is expressed in liver. TWIK-2 is inhibited by intracellular, but not extracellular, acidification.Synonyms: HOHO1, Inward rectifying potassium channel protein TWIK-1, KCNK1, KCNO1, Potassium channel KCNO1, Potassium channel subfamily K member 1, TWIK1
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分子量
- approx. 38 kDa
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基因ID
- 3775
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NCBI登录号
- NP_002236
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UniProt
- O00180
抗原
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