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CYB5R3 抗体

The 兔 多克隆 anti-CYB5R3 antibody is suitable to detect CYB5R3 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN317921
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CYB5R3 抗体 (ABIN317921)

抗原

See all CYB5R3 抗体
CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

适用

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宿主

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克隆类型

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多克隆

标记

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This CYB5R3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    CYB5R3 antibody detects endogenous levels of CYB5R3 protein.(region surrounding Ile169)

    纯化方法

    Affinity Chromatography.
  • 应用备注

    ELISA: 1/40000approx. 1/60000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))

    别名

    CYB5R3

    背景

    CYB5R3 (NADH-cytochrome b5, reductase 3, diaphorase 1) is a 301 amino acid protein encoded by the human gene CYB5R3. CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms. Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane,while isoform 2 is the soluble form found in erythrocytes. CYB5R3 is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis,drug metabolism and, in erythrocytes, methemoglobin reduction. A serine residue at position 117 seems to only be found in persons of African origin. The allele frequency is 0.23 in African Americans. It is not found in Caucasians,Asians, Indo-Aryans or Arabs. This difference seems to have no effect on the enzyme activity.Synonyms: B5R, DIA1, Diaphorase-1, NADH-cytochrome b5 reductase 3

    分子量

    approx. 34 kDa

    基因ID

    1727

    NCBI登录号

    NP_000389

    UniProt

    P00387

    途径

    SARS-CoV-2 Protein Interactome
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