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VIPR1 抗体

VIPR1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317871
发货至: 中国
  • 抗原 See all VIPR1 抗体
    VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))
    适用
    • 48
    • 26
    • 26
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 63
    • 2
    • 1
    克隆类型
    • 66
    多克隆
    标记
    • 27
    • 5
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    This VIPR1 antibody is un-conjugated
    应用范围
    • 56
    • 25
    • 22
    • 22
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of VPAC1 protein. (region surrounding Val371)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product VIPR1 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    PBS, pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))
    Abstract
    VIPR1 产品
    别名
    HVR1 antibody, II antibody, PACAP-R-2 antibody, PACAP-R2 antibody, RDC1 antibody, V1RG antibody, VAPC1 antibody, VIP-R-1 antibody, VIPR antibody, VIRG antibody, VPAC1 antibody, VPAC1R antibody, VPCAP1R antibody, CVIPR antibody, AV071699 antibody, VIP-R1 antibody, RATVASREC antibody, VASREC antibody, VIPR1 antibody, LOC100226500 antibody, vipr1 antibody, hvr1 antibody, rdc1 antibody, v1rg antibody, vipr antibody, virg antibody, vapc1 antibody, vpac1 antibody, vpcap1 antibody, vpac1-r antibody, VIP-R antibody, vasoactive intestinal peptide receptor 1 antibody, vasoactive intestinal peptide receptor 1b antibody, vasoactive intestinal peptide receptor 1 S homeolog antibody, vasoactive intestinal polypeptide receptor antibody, VIPR1 antibody, Vipr1 antibody, vipr1b antibody, vipr1 antibody, vipr1.S antibody, LOC100303683 antibody
    背景
    The vasoactive intestinal peptide (VIP) and the pituitary adenylate cylaseactivating polypeptide (PACAP) belong to a superfamily of peptide hormones that include glucagon, secretin and growth hormone releasing hormone. The effects of VIP and PACAP are mediated by three G-protein coupled receptors, VPAC1, VPAC2 and the PACAP receptor (also designated PAC1-R). The VPAC receptors have equal affinities for VIP and PACAP, which stimulate the activation of adenylyl cyclase. Both VPAC1, a 47 kDa protein, and VPAC2, a 65 kDa protein, are abundantly expressed in brain and T cells, where they modulate neuronal differentiation and T cell activation, respectively. The PACAP receptor is a seven transmembrane protein that produces at least eight isoforms by alternative splicing. Each isoform is associated with a specific signaling pathway and a specific expression pattern. The PACAP receptor, which is thought to play an integral role in brain development, preferentially binds PACAP in order to stimulate a cAMP-protein kinase A signaling pathway.Synonyms: PACAP-R-2, PACAPR2, Pituitary adenylate cyclase-activating polypeptide type II receptor, VIP-R1, VIPR-1, VIPR1, Vasoactive intestinal polypeptide receptor 1
    分子量
    approx. 52 kDa
    基因ID
    7433
    NCBI登录号
    NP_004615
    UniProt
    P32241
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