CLCN4 抗体
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- 抗原 See all CLCN4 抗体
- CLCN4 (Chloride Channel 4 (CLCN4))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CLCN4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- This antibody detects endogenous levels of CLC-4 protein.(region surrounding Glu254)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat.
- 纯化方法
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product CLCN4 Primary Antibody
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anti-Chloride Channel 4 (CLCN4) (C-Term) antibody
CLCN4 适用: 人 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 4 (CLCN4) (Internal Region) antibodyCLCN4 适用: 人 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 4 (CLCN4) antibodyCLCN4 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 4 (CLCN4) (Internal Region) antibodyCLCN4 适用: 人, 大鼠, 小鼠 WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 4 (CLCN4) (Internal Region) antibodyCLCN4 适用: 人, 大鼠, 小鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 4 (CLCN4) (AA 663-689), (C-Term) antibodyCLCN4 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB0752 unconjugated
anti-Chloride Channel 4 (CLCN4) (AA 221-270) antibodyCLCN4 适用: 人, 大鼠, 小鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 4 (CLCN4) (C-Term) antibodyCLCN4 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 60000approx. 1: 80000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CLCN4 (Chloride Channel 4 (CLCN4))
- 别名
- CLCN4 (CLCN4 产品)
- 别名
- Clc4-2 antibody, Clcn4 antibody, CLC4 antibody, ClC-4 antibody, ClC-4A antibody, Clcn4-2 antibody, chloride voltage-gated channel 4 antibody, chloride channel, voltage-sensitive 4 antibody, CLCN4 antibody, clcn4 antibody, Clcn4 antibody
- 背景
- The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7, 3q26, 4q32, Xp22, Xp11, 1p36 and 16p13, respectively. CLC-1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC-1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC-2 is highly expressed in the epithelia of several organs including lung, which suggests CLC-2 may be a possible therapeutic target for cystic fibrosis. CLC-3 expression is particularly abundant in neuronal tissue, while CLC-4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC-5 lead to Dent's disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC-6 and CLC-7 are broadly expressed in several tissues including testes, kidney, brain and muscle.Synonyms: CLC4, Chloride channel protein 4, Chloride transporter ClC-4, ClC-4, ClC4, H(+)/Cl(-) exchange transporter 4
- 分子量
- approx. 85 kDa
- 基因ID
- 1183
- NCBI登录号
- NP_001821
- UniProt
- P51793
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