CLCN4 抗体 (AA 221-270)
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Quick Overview for CLCN4 抗体 (AA 221-270) (ABIN1534766)
抗原
See all CLCN4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-270
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原理
- CLC-4 Antibody
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特异性
- CLC-4 Polyclonal Antibody detects endogenous levels of CLC-4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CLCN4. AA range:221-270
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CLCN4 (Chloride Channel 4 (CLCN4))
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别名
- CLCN4
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背景
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Synonyms: CLCN4, H(+)/Cl(-) exchange transporter 4, Chloride channel protein 4, ClC-4, Chloride transporter ClC-4
Background: chloride voltage-gated channel 4(CLCN4) Homo sapiens The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012],
Gene Name: CLCN4
Protein Name: H(+)/Cl(-) exchange transporter 4
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分子量
- 84 kDa
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基因ID
- 1183
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OMIM
- 302910
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UniProt
- P51793
抗原
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