IL4 Receptor 抗体
Our Local Distributor
北京 101111
Quick Overview for IL4 Receptor 抗体 (ABIN317795)
抗原
See all IL4 Receptor (IL4R) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of IL-4R-alpha protein.(region surrounding Gly493)
-
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
-
-
anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibody
IL4R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-233) antibodyIL4R 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 201-300) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, FACS, ICC, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibodyIL4R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4B12B12 unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 1-227) antibodyIL4R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (N-Term) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 677-691), (C-Term) antibodyIL4R 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB48074 unconjugated
anti-Interleukin 4 Receptor (IL4R) antibodyIL4R 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (Ser540) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1: 1000approx. 1: 4000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
-
别名
- CD124 / IL4R
-
背景
- IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.Synonyms: 582J2.1, IL-4R-alpha, IL4 Receptor alpha, IL4RA, Interleukin-4 receptor alpha chain
-
分子量
- approx. 88.0 kDa
-
基因ID
- 3566
-
NCBI登录号
- NP_000409
-
UniProt
- P24394
-
途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
抗原
-
