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CD226 抗体

The 兔 多克隆 anti-CD226 antibody (ABIN317787) specifically detects CD226 in WB 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN317787
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD226 抗体 (ABIN317787)

抗原

See all CD226 抗体
CD226

适用

  • 85
  • 41
  • 7
  • 6
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 68
  • 32
  • 12
  • 1

克隆类型

  • 60
  • 52
  • 1
多克隆

标记

  • 62
  • 10
  • 7
  • 7
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This CD226 antibody is un-conjugated

应用范围

  • 57
  • 48
  • 35
  • 30
  • 25
  • 15
  • 12
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 特异性

    CD226 antibody detects endogenous levels of CD226 protein.(region surrounding Tyr325)

    纯化方法

    Affinity chromatography
  • 应用备注

    ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD226

    别名

    CD226 / DNAM1

    背景

    CD226 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. CD226 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit Tand NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.Synonyms: DNAM-1, DNAX accessory molecule 1

    分子量

    approx. 38 kDa

    基因ID

    10666

    NCBI登录号

    NP_006557

    UniProt

    Q15762

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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