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CD226 抗体

CD226 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317787
发货至: 中国
  • 抗原 See all CD226 抗体
    CD226
    适用
    • 68
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 51
    • 19
    • 3
    克隆类型
    • 47
    • 25
    • 1
    多克隆
    标记
    • 43
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD226 antibody is un-conjugated
    应用范围
    • 40
    • 30
    • 25
    • 13
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    CD226 antibody detects endogenous levels of CD226 protein.(region surrounding Tyr325)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product CD226 Primary Antibody
  • 应用备注
    ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD226
    别名
    CD226 / DNAM1 (CD226 产品)
    别名
    CD226 antibody, cd226 antibody, zgc:158817 antibody, BC051526 antibody, DNAM-1 antibody, DNAM1 antibody, Pta1 antibody, TLiSA1 antibody, PTA1 antibody, CD226 molecule antibody, CD226 antigen antibody, CD226 antibody, cd226 antibody, Cd226 antibody
    背景
    CD226 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. CD226 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit Tand NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.Synonyms: DNAM-1, DNAX accessory molecule 1
    分子量
    approx. 38 kDa
    基因ID
    10666
    NCBI登录号
    NP_006557
    UniProt
    Q15762
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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