PIM1 抗体
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北京 101111
Quick Overview for PIM1 抗体 (ABIN317785)
抗原
See all PIM1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Pim-1 protein.(region surrounding Ile302)
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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ELISA: 1/5000approx. 1/40000. Western Blot: 1/500approx. 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PIM1 (Pim-1 Oncogene (PIM1))
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别名
- PIM1
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背景
- Pim-1 is a serine/threonine kinase that cooperates with c-Myc in lymphoid cell transformation. The expression of Pim-1 increases during the progression from early to late G1, remaining high at the G1/S boundary and G2 phases of the cell cycle. Pim-1 is regulated at both the transcriptional and translational level, and it has been shown to be induced by IL-2 stimulation. Pim-1 also plays a role in T cell differentiation, and it has been shown to stimulate c-Myc-mediated apoptosis upstream of caspase-3-like proteases.Synonyms: Pim-1, Proto-oncogene serine/threonine-protein kinase pim-1
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分子量
- approx. 50 kDa
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基因ID
- 5292
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NCBI登录号
- NP_002639
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UniProt
- P11309
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途径
- Glycosaminoglycan Metabolic Process
抗原
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