OPRK1 抗体
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北京 101111
Quick Overview for OPRK1 抗体 (ABIN317765)
抗原
See all OPRK1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of KOR-1 protein.(region surrounding Arg361)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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应用备注
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ELISA: 1/1000-1/5000. Western blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Evaluation of primary opioid receptor antibodies for use in western blotting." in: British journal of anaesthesia, Vol. 108, Issue 3, pp. 530-2, (2012) (PubMed).
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: "Evaluation of primary opioid receptor antibodies for use in western blotting." in: British journal of anaesthesia, Vol. 108, Issue 3, pp. 530-2, (2012) (PubMed).
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- OPRK1 (Opioid Receptor, kappa 1 (OPRK1))
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别名
- kappa Opioid Receptor
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背景
- Opioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain, consciousness, motor control, mood, and autonomic function, and can induce physical dependence. Pharmacological studies suggested that there are at least 3 major classes of opioid receptors, designated delta, kappa, and mu. They differ in their affinity for various opioid ligands and in their cellular distribution. Studies of the receptors in the mouse and rat show that they are structurally related and are members of the family of 7 transmembrane-spanning G protein-coupled receptors. The kappa opiod receptor inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for beta-endorphin.Synonyms: KOR-1, KOR1, OPRK, OPRK1
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分子量
- approx. 48 kDa
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基因ID
- 4986
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NCBI登录号
- NP_000903
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UniProt
- P41145
抗原
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