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OPRK1 抗体

Cited in 1 publication. This anti-OPRK1 antibody is a 兔 多克隆 antibody detecting OPRK1 in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN317765
发货至: 中国
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Quick Overview for OPRK1 抗体 (ABIN317765)

抗原

See all OPRK1 抗体
OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This OPRK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    This antibody detects endogenous levels of KOR-1 protein.(region surrounding Arg361)

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    ELISA: 1/1000-1/5000. Western blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Niwa, Rowbotham, Lambert: "Evaluation of primary opioid receptor antibodies for use in western blotting." in: British journal of anaesthesia, Vol. 108, Issue 3, pp. 530-2, (2012) (PubMed).

  • 抗原

    OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

    别名

    kappa Opioid Receptor

    背景

    Opioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain, consciousness, motor control, mood, and autonomic function, and can induce physical dependence. Pharmacological studies suggested that there are at least 3 major classes of opioid receptors, designated delta, kappa, and mu. They differ in their affinity for various opioid ligands and in their cellular distribution. Studies of the receptors in the mouse and rat show that they are structurally related and are members of the family of 7 transmembrane-spanning G protein-coupled receptors. The kappa opiod receptor inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for beta-endorphin.Synonyms: KOR-1, KOR1, OPRK, OPRK1

    分子量

    approx. 48 kDa

    基因ID

    4986

    NCBI登录号

    NP_000903

    UniProt

    P41145
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