FFAR1 抗体
Quick Overview for FFAR1 抗体 (ABIN317749)
抗原
See all FFAR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GPR40 protein. (region surrounding Trp224)
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纯化方法
- Affinity chromatography
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anti-Free Fatty Acid Receptor 1 (FFAR1) (AA 143-178) antibody
FFAR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Free Fatty Acid Receptor 1 (FFAR1) (Internal Region) antibodyFFAR1 适用: 人, 猴 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Free Fatty Acid Receptor 1 (FFAR1) (C-Term) antibodyFFAR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Free Fatty Acid Receptor 1 (FFAR1) (C-Term) antibodyFFAR1 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Free Fatty Acid Receptor 1 (FFAR1) (AA 121-220) antibodyFFAR1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Free Fatty Acid Receptor 1 (FFAR1) (C-Term) antibodyVerified FFAR1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Free Fatty Acid Receptor 1 (FFAR1) (Internal Region) antibodyFFAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Free Fatty Acid Receptor 1 (FFAR1) (N-Term) antibodyFFAR1 适用: 人, 小鼠, 大鼠, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Free Fatty Acid Receptor 1 (FFAR1) (N-Term) antibodyFFAR1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Free Fatty Acid Receptor 1 (FFAR1) (AA 185-234) antibodyFFAR1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS, pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
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别名
- FFAR1 / GPR40
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背景
- G protein coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G proteincoupled receptor 40 (GPR40) functions as a cell-surface receptor for longchain free fatty acids (FFAs). FFAs provide an important energy source, but also function as signaling molecules in various pathways, notably the process of insulin secretion. In pancreatic tissue, the interaction of long chain FFAs with GPR40 amplifies glucose-stimulated insulin secretion from beta cells, suggesting a possible role for GPR40 in the treatment of diabetes associated with insulin-deficiency. Specifically, the Arg211His polymorphism in the GPR40 gene may contribute to the variation of insulin secretory capacity in Japanese men. Also, GPR40 may be involved in the control of breast cancer cell growth by fatty acids and, therefore, provide a link between fat and cancer.Synonyms: Free fatty acid receptor 1, G-protein coupled receptor 40
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分子量
- approx. 26 kDa
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基因ID
- 2864
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NCBI登录号
- NP_005294
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UniProt
- O14842
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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