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S1PR3 抗体

This anti-S1PR3 antibody is a 兔 多克隆 antibody detecting S1PR3 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN317744
发货至: 中国

Quick Overview for S1PR3 抗体 (ABIN317744)

抗原

See all S1PR3 抗体
S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This S1PR3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of EDG-3 protein.(region surrounding Phe155)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity-chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/40000-1/60000. Wetren blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

    别名

    EDG-3 / S1P3

    背景

    EDG3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG3 is expressed in heart, placenta, kidney, and liver tissue.Synonyms: EDG3, Endothelial differentiation G-protein coupled receptor 3, FLJ37523, FLJ93220, LPB3, MGC71696, S1P receptor 3, S1PR3, Sphingosine 1-phosphate receptor 3

    分子量

    approx. 42 kDa

    基因ID

    1903

    NCBI登录号

    NP_005217

    UniProt

    Q99500
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