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ADORA1 抗体

This anti-ADORA1 antibody is a 兔 多克隆 antibody detecting ADORA1 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN317738
发货至: 中国

Quick Overview for ADORA1 抗体 (ABIN317738)

抗原

See all ADORA1 抗体
ADORA1 (Adenosine A1 Receptor (ADORA1))

适用

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人, 小鼠

宿主

  • 83
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克隆类型

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多克隆

标记

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This ADORA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of Adenosine A1-R protein.(region surrounding Leu591)

    交叉反应 (详细)

    Species reactivity (tested):Human and Mouse.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ADORA1 (Adenosine A1 Receptor (ADORA1))

    别名

    Adenosine Receptor A1

    背景

    Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA1

    分子量

    approx. 37 kDa

    基因ID

    134

    NCBI登录号

    NP_000665

    UniProt

    P30542

    途径

    EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Synaptic Membrane
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