ADORA1 抗体
Our Local Distributor
北京 101111
Quick Overview for ADORA1 抗体 (ABIN317738)
抗原
See all ADORA1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of Adenosine A1-R protein.(region surrounding Leu591)
-
交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
-
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
-
-
-
-
应用备注
-
ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- ADORA1 (Adenosine A1 Receptor (ADORA1))
-
别名
- Adenosine Receptor A1
-
背景
- Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA1
-
分子量
- approx. 37 kDa
-
基因ID
- 134
-
NCBI登录号
- NP_000665
-
UniProt
- P30542
-
途径
- EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Synaptic Membrane
抗原
-