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O3FAR1 抗体

O3FAR1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317737
发货至: 中国
  • 抗原 See all O3FAR1 抗体
    O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
    适用
    • 61
    • 37
    • 19
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    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 61
    • 1
    • 1
    克隆类型
    • 62
    • 1
    多克隆
    标记
    • 29
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This O3FAR1 antibody is un-conjugated
    应用范围
    • 54
    • 31
    • 13
    • 13
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of GPR120 protein. (region surrounding Val259)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product O3FAR1 Primary Antibody
  • 应用备注
    ELISA: 1/1000-1/10000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
    别名
    GPR120 (O3FAR1 产品)
    别名
    BMIQ10 antibody, GPR120 antibody, GPR129 antibody, GT01 antibody, O3FAR1 antibody, PGR4 antibody, AI552415 antibody, Gpr120 antibody, Gpr129 antibody, KPG_013 antibody, O3far1 antibody, Pgr4 antibody, free fatty acid receptor 4 antibody, phosphodiesterase 6C antibody, FFAR4 antibody, Ffar4 antibody, PDE6C antibody
    背景
    GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of Glucagon-like peptide-1 (GLP-1) in vivo and in vitro.GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake.GLP-1 also inhibits Glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.Synonyms: G-protein coupled receptor 120, GPR129, GT01, PGR4
    分子量
    approx. 38 kDa
    基因ID
    338557
    NCBI登录号
    NP_001182684
    UniProt
    Q5NUL3
    途径
    Hormone Transport
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