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O3FAR1 抗体

This anti-O3FAR1 antibody is a 兔 多克隆 antibody detecting O3FAR1 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN317737
发货至: 中国

Quick Overview for O3FAR1 抗体 (ABIN317737)

抗原

See all O3FAR1 抗体
O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This O3FAR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of GPR120 protein. (region surrounding Val259)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/1000-1/10000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

    别名

    GPR120

    背景

    GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of Glucagon-like peptide-1 (GLP-1) in vivo and in vitro.GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake.GLP-1 also inhibits Glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.Synonyms: G-protein coupled receptor 120, GPR129, GT01, PGR4

    分子量

    approx. 38 kDa

    基因ID

    338557

    NCBI登录号

    NP_001182684

    UniProt

    Q5NUL3

    途径

    Hormone Transport
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