O3FAR1 抗体
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北京 101111
Quick Overview for O3FAR1 抗体 (ABIN317737)
抗原
See all O3FAR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GPR120 protein. (region surrounding Val259)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (N-Term) antibody
O3FAR1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) antibodyO3FAR1 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 22-36), (Extracellular) antibodyO3FAR1 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (Internal Region) antibodyO3FAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 247-258) antibodyO3FAR1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (C-Term) antibodyO3FAR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (Internal Region) antibodyO3FAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (AA 22-36), (Extracellular) antibody (FITC)O3FAR1 适用: 小鼠 FACS 宿主: 兔 Polyclonal FITC
anti-omega-3 Fatty Acid Receptor 1 (O3FAR1) (Internal Region) antibodyVerified O3FAR1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
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ELISA: 1/1000-1/10000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))
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别名
- GPR120
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背景
- GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of Glucagon-like peptide-1 (GLP-1) in vivo and in vitro.GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake.GLP-1 also inhibits Glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.Synonyms: G-protein coupled receptor 120, GPR129, GT01, PGR4
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分子量
- approx. 38 kDa
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基因ID
- 338557
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NCBI登录号
- NP_001182684
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UniProt
- Q5NUL3
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途径
- Hormone Transport
抗原
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