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MAP4K3 抗体

MAP4K3 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317719
发货至: 中国
  • 抗原 See all MAP4K3 抗体
    MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))
    适用
    人, 小鼠, 大鼠
    宿主
    • 57
    • 2
    克隆类型
    • 57
    • 2
    多克隆
    标记
    • 24
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MAP4K3 antibody is un-conjugated
    应用范围
    • 42
    • 33
    • 32
    • 20
    • 7
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    GLK antibody detects endogenous levels of GLK protein.(region surrounding Gly4)
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product MAP4K3 Primary Antibody
  • 应用备注
    ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))
    别名
    MAP4K3 (MAP4K3 产品)
    别名
    GLK antibody, MAPKKKK3 antibody, MEKKK 3 antibody, MEKKK3 antibody, RAB8IPL1 antibody, 4833416M01Rik antibody, 4833416M07Rik antibody, 9530052P13Rik antibody, Glk antibody, mitogen-activated protein kinase kinase kinase kinase 3 antibody, MAP4K3 antibody, Map4k3 antibody
    背景
    Several mammalian kinases have been identified which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase STE20. STE20 is involved in relaying signals from G-protein coupled receptors to cytosolic MAP kinase cascades, and it lies upstream of a MAP kinase kinase kinase. Mammalian STE20-like kinases include GLK, KHS, NIK, YSK1, HPK1, Krs-1, Krs-2 and human GC kinase. GLK (for GC-like kinase) is an 885 amino acid protein that shares a high degree of homology with GC kinase and HPK1. Like many of the STE20-like kinases, GLK specifically activates the JNK pathway. Epistasis studies with dominant negative mutants of MEKK1 suggest that GLK functions upstream of MEKK1 in the JNK signaling pathway.Synonyms: Germinal center kinase-related protein kinase, MAPK, MAPK/ERK kinase kinase kinase 3, MEKKK 3, Mitogen-activated protein kinase kinase kinase kinase 3, RAB8IPL1
    分子量
    approx. 101 kDa
    基因ID
    8491
    NCBI登录号
    NP_003609
    UniProt
    Q8IVH8
    途径
    MAPK Pathway
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