MC1 Receptor 抗体
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北京 101111
Quick Overview for MC1 Receptor 抗体 (ABIN317707)
抗原
See all MC1 Receptor (MC1R) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of MC1-R protein (region surrounding Val312).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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ELISA: 1/1000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))
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别名
- MC1-R
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背景
- The melanocortin family comprises the alpha-, beta- and gamma-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.Synonyms: MC1R, MSH-R, MSHR, Melanocortin receptor 1, Melanocyte-stimulating hormone receptor, Melanotropin receptor
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分子量
- approx. 35 kDa
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基因ID
- 4157
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NCBI登录号
- NP_002377
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UniProt
- Q01726
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途径
- cAMP Metabolic Process, Feeding Behaviour
抗原
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