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MC1 Receptor 抗体

This 兔 多克隆 antibody specifically detects MC1 Receptor in WB, IF 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN317707
发货至: 中国
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Quick Overview for MC1 Receptor 抗体 (ABIN317707)

抗原

See all MC1 Receptor (MC1R) 抗体
MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

适用

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宿主

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克隆类型

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多克隆

标记

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This MC1 Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of MC1-R protein (region surrounding Val312).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/1000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

    别名

    MC1-R

    背景

    The melanocortin family comprises the alpha-, beta- and gamma-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.Synonyms: MC1R, MSH-R, MSHR, Melanocortin receptor 1, Melanocyte-stimulating hormone receptor, Melanotropin receptor

    分子量

    approx. 35 kDa

    基因ID

    4157

    NCBI登录号

    NP_002377

    UniProt

    Q01726

    途径

    cAMP Metabolic Process, Feeding Behaviour
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