RAD51D 抗体
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北京 101111
Quick Overview for RAD51D 抗体 (ABIN317685)
抗原
See all RAD51D 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Rad51D protein.(region surrounding Ala152)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-RAD51 Homolog D (RAD51D) (AA 1-216) antibody
RAD51D 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RAD51 Homolog D (RAD51D) (AA 1-328) antibodyRAD51D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C8-3C12 unconjugated
anti-RAD51 Homolog D (RAD51D) (C-Term) antibodyRAD51D 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog D (RAD51D) (AA 1-328) antibodyRAD51D 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog D (RAD51D) antibodyRAD51D 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5175 unconjugated Recombinant Antibody
anti-RAD51 Homolog D (RAD51D) (AA 1-100) antibodyRAD51D 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog D (RAD51D) (AA 1-216) antibodyRAD51D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog D (RAD51D) (C-Term) antibodyRAD51D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog D (RAD51D) antibodyRAD51D 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-RAD51 Homolog D (RAD51D) (AA 259-308) antibodyRAD51D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2 containing 0,05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RAD51D (RAD51 Homolog D (RAD51D))
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别名
- RAD51L3
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背景
- Rad52 family members (Rad50, Rad51B/C/D, Rad52, Rad54, MRE11) mediate DNA double-strand break repair (DSBR) for DNA damage that otherwise could cause cell death, mutation or neoplastic transformation. Rad51 (RECA, BRCC5) interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of Rad51. Rad52 forms a heptameric ring that binds single-stranded DNA ends and catalyzes DNA-DNA interaction necessary for the annealing of complementary strands. Rad52 can interact with Rad51. Rad54A of the DEAD-like helicase superfamily binds to double-strand DNA and induces a DNA topological change, which is thought to facilitate homologous DNA pairing and stimulate DNA recombination. Rad54B of the DEAD-like helicase superfamily binds to double-stranded DNA and displays ATPase activity in the presence of DNA. Rad54B is abundant in testis and spleen, and mutations of this gene occur in primary lymphoma and colon cancer.Synonyms: DNA repair protein RAD51 homolog 4, R51H3, RAD51 homolog D, RAD51-like protein 3, RAD51D, TRAD
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分子量
- approx. 40 kDa
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基因ID
- 5892
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NCBI登录号
- NP_001136043
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UniProt
- O75771
抗原
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