IL7R 抗体
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北京 101111
Quick Overview for IL7R 抗体 (ABIN317658)
抗原
See all IL7R 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of IL-7R protein.(region surrounding Gln445)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL7R (Interleukin 7 Receptor (IL7R))
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别名
- CD127 / IL7R
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背景
- The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. The functional high-affinity IL7 receptor consists of an alpha chain and a gamma chain. Both IL7R alpha and IL7R gamma are members of the hematopoietin receptor superfamily. IL7R alpha cDNA encodes a precursor protein containing a signal peptide, an extracellular ligand binding domain, a transmembrane region, and a cytoplasmic region. IL7R alpha transcripts have been observed in spleen, thymus, fetal liver, developing T cells, B cells, mature T cells, and bone marrow derived macrophages.Synonyms: IL-7R-alpha, IL7 receptor alpha, Interleukin-7 receptor subunit alpha
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分子量
- approx. 52 kDa
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基因ID
- 3575
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NCBI登录号
- NP_002176
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UniProt
- P16871
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
抗原
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