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IL7R 抗体

The 兔 多克隆 anti-IL7R antibody (ABIN317658) specifically detects IL7R in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN317658
发货至: 中国
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Quick Overview for IL7R 抗体 (ABIN317658)

抗原

See all IL7R 抗体
IL7R (Interleukin 7 Receptor (IL7R))

适用

  • 156
  • 68
  • 37
  • 7
  • 4
  • 2
  • 1
人, 小鼠

宿主

  • 100
  • 60
  • 35
  • 6
  • 1
  • 1

克隆类型

  • 114
  • 84
  • 3
多克隆

标记

  • 88
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  • 3
  • 3
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  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This IL7R antibody is un-conjugated

应用范围

  • 123
  • 109
  • 50
  • 26
  • 26
  • 22
  • 19
  • 13
  • 10
  • 8
  • 7
  • 3
  • 2
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Western Blotting (WB)
  • 特异性

    This antibody detects endogenous levels of IL-7R protein.(region surrounding Gln445)

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    IL7R (Interleukin 7 Receptor (IL7R))

    别名

    CD127 / IL7R

    背景

    The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. The functional high-affinity IL7 receptor consists of an alpha chain and a gamma chain. Both IL7R alpha and IL7R gamma are members of the hematopoietin receptor superfamily. IL7R alpha cDNA encodes a precursor protein containing a signal peptide, an extracellular ligand binding domain, a transmembrane region, and a cytoplasmic region. IL7R alpha transcripts have been observed in spleen, thymus, fetal liver, developing T cells, B cells, mature T cells, and bone marrow derived macrophages.Synonyms: IL-7R-alpha, IL7 receptor alpha, Interleukin-7 receptor subunit alpha

    分子量

    approx. 52 kDa

    基因ID

    3575

    NCBI登录号

    NP_002176

    UniProt

    P16871

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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