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Adenosine A3 Receptor 抗体

ADORA3 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317625
发货至: 中国
  • 抗原 See all Adenosine A3 Receptor (ADORA3) 抗体
    Adenosine A3 Receptor (ADORA3)
    适用
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    宿主
    • 31
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    克隆类型
    • 32
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    多克隆
    标记
    • 25
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    This Adenosine A3 Receptor antibody is un-conjugated
    应用范围
    • 19
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of Adenosine A3-R protein.(region surrounding Glu318)
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product ADORA3 Primary Antibody
  • 应用备注
    ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Adenosine A3 Receptor (ADORA3)
    别名
    Adenosine Receptor A3 (ADORA3 产品)
    背景
    Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthesis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFalpha and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA3, Adenosine A3 receptor
    分子量
    approx. 38 kDa
    基因ID
    140
    NCBI登录号
    NP_000668
    UniProt
    P33765
    途径
    Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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