Serotonin Receptor 2B 抗体
Quick Overview for Serotonin Receptor 2B 抗体 (ABIN317623)
抗原
See all Serotonin Receptor 2B (HTR2B) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of SR-2B protein. (region surrounding His55)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Serotonin Receptor 2B (HTR2B) (Internal Region) antibody
HTR2B 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (N-Term) antibodyHTR2B 适用: 人, Cow, 犬, 豚鼠, Pig, 马 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 382-481) antibodyHTR2B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 408-435), (C-Term) antibodyHTR2B 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB20470 unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 1-56) antibodyHTR2B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 382-481) antibodyHTR2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 261-310) antibodyHTR2B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (N-Term) antibodyHTR2B 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 15-64) antibodyHTR2B 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 2B (HTR2B) (AA 1-56) antibodyHTR2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A4 unconjugated
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应用备注
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ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Serotonin Receptor 2B (HTR2B)
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背景
- Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to serotonin. SR-2A has a specific role in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia. SR-2B is expressed in embryonic and adult cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders. SR-2C is thought to mediate the effects of atypical antipsychotic drugs.Synonyms: 5-HT-2B, 5-HT2B, 5-hydroxytryptamine receptor 2B
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分子量
- approx. 54 kDa
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基因ID
- 3357
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NCBI登录号
- NP_000858
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UniProt
- P41595
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途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
抗原
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