Prothrombin 抗体
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北京 101111
Quick Overview for Prothrombin 抗体 (ABIN317606)
抗原
See all Prothrombin (F2) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Prothrombin protein.(region surrounding Gly724)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Coagulation Factor II (thrombin) (F2) (AA 263-362) antibody
F2 适用: 人 WB, IP, ELISA, RNAi, PLA 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 324-617) antibodyF2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 44-200) antibodyF2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (Middle Region) antibodyF2 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) antibodyF2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal E1 unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 44-200) antibodyF2 适用: 大鼠 WB 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Coagulation Factor II (thrombin) (F2) (Internal Region) antibodyF2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 1-622) antibodyF2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (N-Term) antibodyF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) (F2) (AA 67-124) antibodyF2 适用: 人 WB, IHC, ICC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500-1/1000. ELISA: 1/10000-1/20000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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别名
- Prothrombin (F2)
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背景
- Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which mediate a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Proteolytic cleavage of Prothrombin (Factor II) at residue 44 leads to formation of Thrombin in the first step of the coagulation cascade. Thrombin cleaves bonds between Arg and Gly and activates Factors V, VII, VIII and XIII in complex with thrombomodulin and Protein C. Thrombin maintains vascular integrity during development and postnatal life and coordinates connective tissue proteins by stimulating fibroblast procollagen production.Synonyms: Coagulation factor II
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分子量
- approx. 70 kDa
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基因ID
- 2147
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NCBI登录号
- NP_000497
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UniProt
- P00734
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途径
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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