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LTBR 抗体 (Extracellular Domain) (PE)

This anti-LTBR antibody is a 大鼠 单克隆 antibody detecting LTBR in FACS. Suitable for 小鼠.
产品编号 ABIN317402
发货至: 中国

Quick Overview for LTBR 抗体 (Extracellular Domain) (PE) (ABIN317402)

抗原

See all LTBR 抗体
LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

适用

  • 70
  • 49
  • 1
小鼠

宿主

  • 55
  • 20
  • 19
  • 1
大鼠

克隆类型

  • 57
  • 36
单克隆

标记

  • 58
  • 8
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LTBR antibody is conjugated to PE

应用范围

  • 58
  • 32
  • 26
  • 16
  • 13
  • 13
  • 10
  • 8
  • 8
  • 7
  • 4
  • 3
  • 2
  • 2
Flow Cytometry (FACS)

克隆位点

5G11b
  • 抗原表位

    • 15
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    Extracellular Domain

    特异性

    This antibody recognises lymphotoxin-beta receptor (LT beta R), a member of the tumour necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognises surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (2). This product is routinely tested on mouse WEHI cells.

    产品特性

    Synonyms: Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR,TNFRSF3, D12S370, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamilymember 3, Tumor necrosis factor receptor type III, Tumor necrosis factor receptor 2-relatedprotein

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    免疫原

    Recombinant extracellular domain of LT beta R

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Reconstitute with 1.0 mL distilled water

    浓度

    0.05 mg/mL

    缓冲液

    Phosphate buffered saline pH 7.4, 0.09 % Sodium Azide, 1 % Bovine Serum Albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody prior and following reconstitution at 2-8 °C. DO NOT FREEZE. This product is photosensitive and should be protected from light.
    Shelf life: One year from despatch.

    有效期

    12 months
  • 抗原

    LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

    别名

    LTBR / TNFR3

    背景

    The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.Synonyms: D12S370, Lymphotoxin-beta receptor, TNF-R3, TNFCR, TNFRSF3, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor 3, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor type III

    基因ID

    4055

    UniProt

    P36941

    途径

    NF-kappaB Signaling
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