Annexin V 抗体 (Biotin)
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- 抗原 See all Annexin V (ANXA5) 抗体
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Annexin V antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody specifically recognises Annexin V. Clone VAA-33 has been reported to work in western blotting applications.
- 产品特性
- Synonyms: Annexin-5, Annexin V, Lipocortin V, Endonexin II, Calphobindin I, Anchorin CII, ANX5, ENX2,PP4, CBP-I, PAP-I, VAC-alpha, Placental anticoagulant protein I, Placental anticoagulantprotein 4, Thromboplastin inhibitor, Vascular anticoagulant-alpha
- 纯化方法
- Purified IgG prepared by affinity chromatography on Protein G
- 免疫原
- Recombinant Annexin V
- 克隆位点
- VAA-33
- 亚型
- IgG2a
- Top Product
- Discover our top product ANXA5 Primary Antibody
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- 应用备注
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Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0,2 mg/mL
- 缓冲液
- 50 mM Tris, 100 mM Nacl pH 7.4 containing 0.02 % Sodium Azide (NaN3), 1 % Bovine Serum Albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
- 别名
- Annexin A5 / ANXA5 (ANXA5 产品)
- 背景
- AnnexinV is a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc).Synonyms: ANX5, Anchorin CII, Annexin V, Annexin-5, CBP-I, Calphobindin I, ENX2, Endonexin II, Lipocortin V, PAP-I, PP4, Placental anticoagulant protein 4, Placental anticoagulant protein I, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha
- 基因ID
- 308
- UniProt
- P08758
- 途径
- Apoptosis
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