-
- 抗原 See all IRF3 抗体
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
-
抗原表位
- AA 108-166
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This IRF3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- The antibody recognizes human interferon regulatory factor 3 (IRF3), a 55 kDa constitutively expressed member of the IRF family. Other species not tested.
- 产品特性
- Synonyms: Interferon regulatory factor 3, IRF-3
- 纯化方法
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- 免疫原
- Recombinant human IRF3 (108-166 aa) purified from E. coli
- 克隆位点
- 3F10
- 亚型
- IgG1
- Top Product
- Discover our top product IRF3 Primary Antibody
-
anti-Interferon Regulatory Factor 3 (IRF3) (pSer396) antibody
IRF3 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) antibodyIRF3 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-260) antibodyIRF3 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibodyIRF3 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C8 unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 51-150) antibodyIRF3 适用: 人, 小鼠, 大鼠, 猴, Cow WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-360) antibodyIRF3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (C-Term) antibodyIRF3 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (pSer386) antibodyIRF3 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) antibodyIRF3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 4C3 unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1268-1341) antibodyIRF3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA. Western blot (1: 1,000 - 1: 3,000), recommended starting dilution is 1: 2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.4, containing 10 % glycerol and 0.01 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
-
- 抗原
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- 别名
- IRF3 (IRF3 产品)
- 别名
- irf3 antibody, IRF3 antibody, C920001K05Rik antibody, IRF-3 antibody, interferon regulatory factor 3 antibody, interferon regulatory factor 7 antibody, irf3 antibody, IRF3 antibody, irf-3 antibody, Irf3 antibody, IRF7 antibody
- 背景
- Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection. IRF3 accumulates in an inactive form in the cytoplasm and then translocates to the nucleus as a homodimer, following stimuli-induced phosphorylation of specific serine/threonine residues. Association of the homodimer with p300/CBP (CREBB binding protein) forms dsRNA-activated factor 1 (DRAF1), which then activates the transcription of interferon alpha and beta, along with other interferon-induced genes.Synonyms: IRF-3, Interferon regulatory factor 3
- 基因ID
- 3661
- UniProt
- Q14653
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
-
You are here:
