BAFF 抗体
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北京 101111
Quick Overview for BAFF 抗体 (ABIN317073)
抗原
See all BAFF (TNFSF13B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody specifically recognises CD257 (otherwise known as BAFF/BLyS). This antibody has not been cross-adsorbed and may react with homologous proteins from related species.
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产品特性
- Synonyms: TNFSF13B, BLYS, TALL1, TNFSF20, ZTNF4, Tumor necrosis factor ligand superfamily member13B, TNF- and APOL-related leukocyte expressed ligand 1, B lymphocyte stimulator, Bcell-activating factor, BAFF, Dendritic cell-derived TNF-like molecule
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纯化方法
- Purified IgG prepared by affinity chromatography on Protein A
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免疫原
- Recombinant full-length mature human CD257 expressed in E. coli.
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亚型
- IgG1
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应用备注
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ELISA: 5 - 6g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Reconstitute with 0.5 mL distilled water
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浓度
- 1.0mg/mL
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缓冲液
- Phosphate buffered saline pH 7.2
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储存条件
- 4 °C/-20 °C
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储存方法
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Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: -
有效期
- 12 months
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- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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别名
- CD257 / BAFF
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背景
- CD257 is a 285 amino acid type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, which acts as a B and T cell stimulator and plays a role in the development of autoimmune diseases such as systemic lupus erythematosus. CD257 is expressed by monocytes, macrophages, T cells and dendritic cells and acts through binding to CD267 (TACI), CD269 (BCMA) and CD268 (BAFFR) receptors, the latter interaction playing a critical role in the activation, survival, differentiation and proliferation of B cells.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4
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基因ID
- 10673
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UniProt
- Q9Y275
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
抗原
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