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PD-1 抗体

PDCD1 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal RMP1-30 unconjugated
产品编号 ABIN316894
发货至: 中国
  • 抗原 See all PD-1 (PDCD1) 抗体
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    适用
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    小鼠
    宿主
    • 85
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    大鼠
    克隆类型
    • 141
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    单克隆
    标记
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    This PD-1 antibody is un-conjugated
    应用范围
    • 131
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises CD279, a 55 kDa cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.
    产品特性
    Synonyms: Protein PD-1, hPD-1, PDCD1, Programmed cell death protein 1
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    免疫原
    PD-1 transferred BHK cells
    克隆位点
    RMP1-30
    亚型
    IgG2b
    Top Product
    Discover our top product PDCD1 Primary Antibody
  • 应用备注
    Flow Cytometry: 1/100 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
    有效期
    12 months
  • 抗原
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    别名
    CD279 / PD1 (PDCD1 产品)
    背景
    CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1
    基因ID
    18566
    UniProt
    Q02242
    途径
    Cancer Immune Checkpoints
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