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P-Selectin 抗体

This anti-P-Selectin antibody is a 小鼠 单克隆 antibody detecting P-Selectin in FACS, IP 和 IHC (p). Suitable for 人, Pig 和 绵羊.
产品编号 ABIN316863
发货至: 中国

Quick Overview for P-Selectin 抗体 (ABIN316863)

抗原

See all P-Selectin (SELP) 抗体
P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

适用

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人, Pig, 绵羊

宿主

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小鼠

克隆类型

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单克隆

标记

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This P-Selectin antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

Psel-KO-2-5
  • 特异性

    This antibody recognises the CD62P cell surface antigen, a 140 kDa glycoprotein also known as P-selectin.

    产品特性

    Synonyms: SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3, Granule membrane protein 140,Leukocyte-endothelial cell adhesion molecule 3, CD62 antigen-like family member P

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    免疫原

    CD62P transfected 300. 19 cells.

    亚型

    IgG1
  • 应用备注

    Immunoprecipitation. Flow Cytometry: Use 10 μL of 1/1-1/50 diluted antibody to label 10^6 cells in 100 μL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

    别名

    CD62P / P-Selectin

    背景

    SELP encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. CD62P is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

    基因ID

    6403

    UniProt

    P16109
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