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CD8 抗体

This 小鼠 单克隆 antibody specifically detects CD8 in IHC (fro). It exhibits reactivity toward 人.
产品编号 ABIN316755
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD8 抗体 (ABIN316755)

抗原

See all CD8 抗体
CD8

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 antibody is un-conjugated

应用范围

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Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

4B11
  • 特异性

    This antibody recognizes the Human CD8 cell surface antigen, a 32 kDa glycoprotein expressed by the cytotoxic/suppressor subset of T-cells and weakly by NK cells. Clone 4B11 has been reported as being suitable for use in Western blotting. AM05530SU-N is recommended for this purpose.

    产品特性

    Synonyms: T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain

    免疫原

    Synthetic peptide derived from CD8 alpha chain sequence.

    亚型

    IgG2b
  • 应用备注

    Immunohistochemistry on Frozen Sections: 1/20-1/40. Immunohistochemistry on paraffin sections: 1/20-1/40. This product requires antigenretrieval using heat treatment prior to staining of paraffin sections.1 mM EDTA pH 8.0 isrecommended for this purpose. Positive Control Tissue: Human Tonsil.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Restore with 1 mL distilled water.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one monthor (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD8

    别名

    CD8

    背景

    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

    基因ID

    925

    UniProt

    P01732
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