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CD70 抗体

CD70 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal Bu69 unconjugated
产品编号 ABIN316748
发货至: 中国
  • 抗原 See all CD70 抗体
    CD70 (CD70 Molecule (CD70))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD70 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognizes CD70, a 29 kDa type II transmembrane protein that belongs to the tumour necrosis factor (TNF) family. CD70 is expressed on a small number of activated T-cells and the majority of activated B-cells. Interaction of CD70 with its receptor, CD27, is thought to play an important role in lymphocyte activation, proliferation, survival and differentiation.
    产品特性
    Synonyms: CD27 ligand, CD27L, CD27LG, TNFSF7, Tumor necrosis factor ligand superfamily member 7
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    克隆位点
    Bu69
    亚型
    IgG1
    Top Product
    Discover our top product CD70 Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections. Flow Cytometry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containssodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled bytrained staff only.
    有效期
    12 months
  • 抗原
    CD70 (CD70 Molecule (CD70))
    别名
    CD70 (CD70 产品)
    背景
    CD70 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.Synonyms: CD27 ligand, CD27L, CD27LG, TNFSF7, Tumor necrosis factor ligand superfamily member 7
    基因ID
    970
    UniProt
    P32970
    途径
    Cancer Immune Checkpoints
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