SMO 抗体
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北京 101111
Quick Overview for SMO 抗体 (ABIN307155)
抗原
See all SMO 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti Human SMO (Smoothened Homolog)
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交叉反应
- 人
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产品特性
- SMO is a G protein-coupled receptor (GPCR) that putatively associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. The binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). In basal cell carcinoma there are two somatic mutations SMO, D473-> H473 and R562 ->Q562.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Synthetic peptide derived from the human SMO protein
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亚型
- IgG
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应用备注
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SMO (Smoothened Homolog (Drosophila) (SMO))
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别名
- SMO (Smoothened Homolog)
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背景
- Smoothened homolog [Precursor], SMO, Gx protein, SMO, SMOH
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UniProt
- Q99835
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途径
- Hedgehog Signaling
抗原
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