CERS6 抗体
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北京 101111
Quick Overview for CERS6 抗体 (ABIN307137)
抗原
See all CERS6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti Human Lass6
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交叉反应
- 人
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产品特性
- Longevity assurance genes (LAGs) represent a subgroup of the homeobox gene family. Five mammalian homologs have been reported, and the corresponding proteins have previously been investigated with respect to their key role in ceramide synthesis. However, members of the LAG family have been shown to be involved in cell growth regulation and cancer differentiation. May be involved in sphingolipid synthesis or its regulation. Interacts with ATP6V0C, ASGR1, ASGR2 and SLC22A1/OCT1. Localized to nuclear membrane a multi-pass membrane protein, may be expressed on endoplasmic reticulum membrane. Glycosylation on Asn-18 is not necessary for function. Like other LAG family members, the LASS6 protein contained a homeodomain and LAG1 domain. Lass6 displays highest homology to LASS5. The corresponding gene was localized to human chromosome 2q24.3, spanning a rather large genomic region of 318 kb. Sequences in mouse and zebrafish suggested a conservation of LASS6 in vertebrates because the protein and corresponding genomic sequences are highly conserved. LASS6 was shown to be broadly expressed in a wide range of tissues. Recent data suggested a role in cancer differentiation and early embryonic development.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Synthetic peptide dervied from human Lass6 protein
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anti-Ceramide Synthase 6 (CERS6) (AA 62-131) antibody
CERS6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5H7 unconjugated
anti-Ceramide Synthase 6 (CERS6) (AA 62-131) antibodyCERS6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B8 unconjugated
anti-Ceramide Synthase 6 (CERS6) (AA 62-131) antibodyCERS6 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ceramide Synthase 6 (CERS6) (AA 324-392) antibodyCERS6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Synthase 6 (CERS6) (N-Term) antibodyCERS6 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, Hamster, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Synthase 6 (CERS6) (N-Term) antibodyCERS6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Synthase 6 (CERS6) (AA 335-361), (C-Term) antibodyCERS6 适用: 人 WB 宿主: 兔 Polyclonal RB37704 unconjugated
anti-Ceramide Synthase 6 (CERS6) (N-Term) antibodyCERS6 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Synthase 6 (CERS6) (N-Term) antibodyCERS6 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Synthase 6 (CERS6) (N-Term) antibodyCERS6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Antibody can be used for Western blotting (5-7 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CERS6 (Ceramide Synthase 6 (CERS6))
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别名
- Lass6
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背景
- LAG1 longevity assurance homolog 6
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UniProt
- Q6ZMG9
抗原
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