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CERS6 抗体 (AA 62-131)

CERS6 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 5H7 unconjugated
产品编号 ABIN566979
发货至: 中国
  • 抗原 See all CERS6 抗体
    CERS6 (Ceramide Synthase 6 (CERS6))
    抗原表位
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 1
    AA 62-131
    适用
    • 35
    • 13
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 32
    • 3
    小鼠
    克隆类型
    • 33
    • 2
    单克隆
    标记
    • 14
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CERS6 antibody is un-conjugated
    应用范围
    • 24
    • 22
    • 4
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Mouse monoclonal antibody raised against a partial recombinant LASS6.
    序列
    PCAIALNIQA NGPQIAPPNA ILEKVFTAIT KHPDEKRLEG LSKQLDWDVR SIQRWFRQRR NQEKPSTLTR
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    LASS6 (NP_982288, 62 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    5H7
    亚型
    IgG2a
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Suzuki, Cao, Kato, Komizu, Mizutani, Tanaka, Arima, Tai, Yanagisawa, Togawa, Shiraishi, Usami, Taniguchi, Fukui, Yokoi, Wakahara, Hasegawa, Mizutani, Igarashi, Inokuchi, Iwaki, Fujii, Satou et al.: "Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells. ..." in: The Journal of clinical investigation, Vol. 126, Issue 1, pp. 254-65, (2016) (PubMed).

    Gerl, Bittl, Kirchner, Sachsenheimer, Brunner, Lüchtenborg, Özbalci, Wiedemann, Wegehingel, Nickel, Haberkant, Schultz, Krüger, Brügger: "Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153009, (2016) (PubMed).

    Jensen, Calvert, Volpert, Kouri, Hurley, Luciano, Wu, Chalastanis, Futerman, Stegh: "Bcl2L13 is a ceramide synthase inhibitor in glioblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 15, pp. 5682-7, (2014) (PubMed).

    Laviad, Kelly, Merrill, Futerman: "Modulation of ceramide synthase activity via dimerization." in: The Journal of biological chemistry, Vol. 287, Issue 25, pp. 21025-33, (2012) (PubMed).

    Yamane, Miyazawa, Moriya, Abe, Yamane et al.: "D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein ..." in: Biochimie, Vol. 93, Issue 9, pp. 1446-59, (2011) (PubMed).

    Mesicek, Lee, Feldman, Jiang, Skobeleva, Berdyshev, Haimovitz-Friedman, Fuks, Kolesnick: "Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells." in: Cellular signalling, Vol. 22, Issue 9, pp. 1300-7, (2010) (PubMed).

    in: (PubMed).

  • 抗原
    CERS6 (Ceramide Synthase 6 (CERS6))
    别名
    LASS6 (CERS6 产品)
    别名
    si:ch211-278b7.1 antibody, CERS6 antibody, CERS5 antibody, LASS6 antibody, 4732462C07Rik antibody, AW544719 antibody, Lass6 antibody, T1L antibody, RGD1561599 antibody, ceramide synthase 6 antibody, CERS6 antibody, cers6 antibody, Cers6 antibody
    背景
    Full Gene Name: LAG1 homolog, ceramide synthase 6
    Synonyms: CerS6,MGC129949,MGC129950
    基因ID
    253782
    NCBI登录号
    NM_203463
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