HNRNPK 抗体 (C-Term)
Quick Overview for HNRNPK 抗体 (C-Term) (ABIN307124)
抗原
See all HNRNPK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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交叉反应
- 小鸡, 人, 小鼠, 兔, 大鼠
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产品特性
- hnRNP-K, CSBP, TUNP, dC-Stretch Binding Protein,Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA Polymerase II. There are approximately 20 known hnRNP proteins, which range in size from 34 kDa to 120 kDa, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm, such as hnRNP K. hnRNP K, a 65 kDa protein, recruits a variety of molecular partners through two K homologous (KH) domains, which are required for protein-protein interactions. hnRNP K also contains several potential phosphorylation sites, including Ser 302, the major site of PKCd phosphorylation, which are thought to regulate various cellular functions, including sequence-specific DNA binding, transcription, RNA binding and nucleocytoplasmic shuttling.
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纯化方法
- Protein A/G Chromatography
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免疫原
- Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminal of the hnRNP-K protein and mouse myeloma Ag8563 cells. Sequence common in human, mouse, rat, rabbit and chicken
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亚型
- IgG1
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anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-280) antibody
HNRNPK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Monoclonal 3G7 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, Cow, 非洲爪蟾, Hamster WB, IHC, ELISA, IF, IP, ICC, FACS, ChIP 宿主: 小鼠 Monoclonal 3C2 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-463) antibodyHNRNPK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (pSer284) antibodyHNRNPK 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 371-420) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 斑马鱼, 小鸡, 豚鼠, 山羊, 马, 猴, 非洲爪蟾, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 小鸡, 豚鼠, 山羊, 马, 猴, 非洲爪蟾, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (C-Term) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Antibody can be used for Western blotting (1-2 μg/mL) and immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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别名
- Heterogeneous Nuclear Ribonucleoprotein K
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UniProt
- P61978
抗原
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