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TIMP2 抗体

TIMP2 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3A4 unconjugated
产品编号 ABIN307122
发货至: 中国
  • 抗原 See all TIMP2 抗体
    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TIMP2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    小鸡, 人, 小鼠, Pig, 兔, 斑马鱼
    产品特性
    CSC-21K, Metalloproteinase Inhibitor 2 precursor,TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases,gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation,branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.
    纯化方法
    Protein A/G Chromatography
    免疫原
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the human TIMP-2 protein and mouse myeloma Ag8563 cells. Sequence common in mouse, rabbit, chicken, zebrafish and pig.
    克隆位点
    3A4
    亚型
    IgG2a
    Top Product
    Discover our top product TIMP2 Primary Antibody
  • 应用备注
    Antibody can be used for ELISA, Western blotting (1-2 μg/mL) and immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
    别名
    Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2) (TIMP2 产品)
    UniProt
    P16035
    途径
    cAMP Metabolic Process
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