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CSAG2 抗体

This anti-CSAG2 antibody is a 兔 多克隆 antibody detecting CSAG2 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN307032
发货至: 中国

Quick Overview for CSAG2 抗体 (ABIN307032)

抗原

See all CSAG2 抗体
CSAG2 (CSAG Family, Member 2 (CSAG2))

适用

宿主

  • 10

克隆类型

  • 10
多克隆

标记

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
This CSAG2 antibody is un-conjugated

应用范围

  • 10
  • 8
  • 7
  • 2
  • 1
Western Blotting (WB), ELISA
  • 交叉反应

    产品特性

    Chondrosarcoma-associated protein 2, Taxol-resistant-associated protein 3, TRAG-3, CSAG2, TRAG3,The expression of the cancer-testis antigen Taxol resistance-associated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR(10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer. First identified as a novel cancer/testis antigen, TRAG-3, (Taxol Resistance Associated Gene-3) was initially discovered in a search for new genes involved in drug resistance. Early studies of TRAG-3 revealed a minimal to absent expression in normal tissues and a marked over-expression in many carcinoma cell lines including several melanoma lines. By RT-PCR evaluation of TRAG-3 two transcripts are seen in many carcinoma cell lines with products in the the 799 bp and a second alternatively spliced transcript.

    纯化方法

    Ammonium Sulfate Precipitation

    免疫原

    Synthetic peptide derived from the human Trag-3 protein.

    亚型

    IgG
  • 应用备注

    Antibody can be used for Western blotting (0.5-2 μg/mL). Optimal concentration should be evaluated by serial dilutions.

    限制

    仅限研究用
  • 缓冲液

    Provided as solution in phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原

    CSAG2 (CSAG Family, Member 2 (CSAG2))

    别名

    Trag 3 (Taxol-resistant-associated protein 3)

    UniProt

    Q9Y5P2
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