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CSAG2 抗体

CSAG2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265187
发货至: 中国
  • 抗原 See all CSAG2 抗体
    CSAG2 (CSAG Family, Member 2 (CSAG2))
    适用
    宿主
    • 16
    克隆类型
    • 16
    多克隆
    标记
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    This CSAG2 antibody is un-conjugated
    应用范围
    • 16
    • 13
    • 13
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Trag 3. Weakly expressed in kidney. Expressed in various tumor cell lines including carcinomas, myeloid and lymphoid malignancies, melanomas and prostate cancer. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40).
    纯化方法
    Purified
    免疫原
    Synthetic peptide derived from the human Trag-3 protein
    亚型
    IgG
    Top Product
    Discover our top product CSAG2 Primary Antibody
  • 应用备注
    Western blot: 0.5-2 μg/mLELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
  • 抗原
    CSAG2 (CSAG Family, Member 2 (CSAG2))
    别名
    CSAG2 (CSAG2 产品)
    别名
    CSAG1 antibody, CSAG3B antibody, CSAG3 antibody, CT24.2 antibody, TRAG-3 antibody, TRAG3 antibody, chondrosarcoma-associated gene 2/3 protein antibody, CSAG family member 2 antibody, LOC705860 antibody, LOC738247 antibody, CSAG2 antibody
    背景
    The expression of the cancer-testis antigen Taxol resistance-associated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR(10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer. First identified as a novel cancer/testis antigen, TRAG-3, (Taxol Resistance Associated Gene-3) was initially discovered in a search for new genes involved in drug resistance. Early studies of TRAG-3 revealed a minimal to absent expression in normal tissues and a marked over-expression in many carcinoma cell lines including several melanoma lines. By RT-PCR evaluation of TRAG-3 two transcripts are seen in many carcinoma cell lines with products in the the 799 bp and a second alternatively spliced transcript.Synonyms: CT24.2, Cancer/testis antigen 24.2, Chondrosarcoma-associated gene 2/3 protein, TRAG-3, TRAG3, Taxol-resistant-associated gene 3 protein
    基因ID
    389903
    NCBI登录号
    NP_001074317
    UniProt
    Q9Y5P2
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