Sphingomyelin Synthase 1 抗体
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Quick Overview for Sphingomyelin Synthase 1 抗体 (ABIN306949)
抗原
See all Sphingomyelin Synthase 1 (SGMS1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit anti Human Sphingomyelin Synthase 1 (Peptide as antigen)
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产品特性
- A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus, Golgi membrane, multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.
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纯化方法
- High Salt Precipitation
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应用备注
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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浓度
- 1 mg/ml
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Sphingomyelin Synthase 1 (SGMS1)
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别名
- Sphingomyelin Synthase 1
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背景
- Phosphatidylcholine:ceramide cholinephosphotransferase 1 Transmembrane protein 23, Sphingomyelin synthase 1, Mob protein
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UniProt
- Q86VZ5
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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