RGR 抗体 (Intracellular)
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Quick Overview for RGR 抗体 (Intracellular) (ABIN306933)
抗原
See all RGR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Intracellular
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交叉反应
- 小鼠, 大鼠
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产品特性
- The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.
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纯化方法
- Protein A/G Chromatography
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免疫原
- Mouse monoclonal antibody raised to a synthetic peptide corresponding to the third intracellular loop of the rat alpha 2b adrenergic receptor.
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亚型
- IgG1
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应用备注
- Antibody detects alpha2B Adrenergic Receptors in Western blots (1-5 μg/mL) and immunohistochemistry. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- RGR (Retinal G Protein Coupled Receptor (RGR))
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别名
- Adrenergic Receptor
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UniProt
- P19328
抗原
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