TYROBP 抗体 (Cytoplasmic Domain)
Quick Overview for TYROBP 抗体 (Cytoplasmic Domain) (ABIN306916)
抗原
See all TYROBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cytoplasmic Domain
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交叉反应
- 人, 小鼠
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产品特性
- TYRO protein tyrosine kinase-binding protein, DNAX-activation protein 12, Killer-activating receptor-associated protein, KARAP, TYROBP,DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells (1,2). DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction (3). Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice (4,5), as well as presenile dementia and bone cysts in humans (6).
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Rabbit immunized with recombinant DAP12 protein (cytoplasmic domain).
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anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (C-Term) antibody
TYROBP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 85-113), (C-Term) antibodyTYROBP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22347 unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 85-113), (C-Term) antibodyTYROBP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 84-113), (C-Term) antibodyTYROBP 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 31-113) antibody (PE)TYROBP 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal PE
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 85-113) antibodyTYROBP 适用: 人 WB, FACS, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (C-Term) antibodyTYROBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (Internal Region) antibodyTYROBP 适用: 人 ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Antibody can be used for immunoprecipitation (2-4 μg/mg of protein lysate). Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
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别名
- DAP12
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UniProt
- O43914
抗原
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