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- 抗原 See all Caspase 7 (CASP7) 抗体
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Caspase 7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 产品特性
- Cysteine-requiring Aspartate Protease-7, Apoptotic protease Mch-3, ICE-like apoptotic protease 3,Caspases are key effectors of programmed cell death. Caspase-7 along with caspase 3 and 6 form the group of effector caspases that are responsible for the cleavage of multiple substrates including the cytokeratins, PARP, alpha fodrin, NuMA and others. Caspase-7 is a 303 amino acid protein with high similarity to caspase-3. Caspase-7 occurs in three varient forms. Granzyme B activates pro-caspase-7 to a form which can cleave poly(ADP-ribose) polymerase (PARP) to its signature fragment of ~85 kDa. Also, in vivo caspase-7 appears to be a better substrate for granzyme B than caspase-3. Pro-caspase-7 has been shown to exist as dimers or high order oligomers. Caspase-7 may be an important intracellular effector of granzyme B-mediated apoptosis and cytotoxic T-lymophocyte-induced cell killing in vivo.
- 纯化方法
- Ammonium Sulfate Precipitation
- 免疫原
- Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human caspase-7 protein and mouse myeloma cells.
- 克隆位点
- MCH3-5
- 亚型
- IgG
- Top Product
- Discover our top product CASP7 Primary Antibody
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anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-303) antibody
CASP7 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 207-303) antibodyCASP7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 29-198) antibodyCASP7 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4D10B2 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyCASP7 适用: 人, 小鼠, 大鼠, 猴, Pig, 犬, Hamster, 兔, 绵羊 WB, IHC (p) 宿主: 小鼠 Monoclonal 7-1-11 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyCASP7 适用: 人, 小鼠, 大鼠, 猴, Pig, 犬, Hamster, 兔, 绵羊 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 7-1-11 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyCASP7 适用: 人, 小鼠, 大鼠, 猴, Hamster WB, IHC (p) 宿主: 小鼠 Monoclonal 10-1-62 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) antibodyCASP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 1-250) antibodyCASP7 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Detects proenzyme form of human Caspase-7 by Western blot. Optimal concentration should be evaluated by serial dilutions.
- 限制
- 仅限研究用
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- 缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- 抗原
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
- 别名
- Caspase-7 (CASP7 产品)
- 别名
- xCaspase-7 antibody, caspase-7 antibody, caspase7 antibody, cmh-1 antibody, ice-lap3 antibody, mch3 antibody, CASP7 antibody, AI314680 antibody, CMH-1 antibody, ICE-IAP3 antibody, Mch3 antibody, mCASP-7 antibody, CASP-7 antibody, ICE-LAP3 antibody, LICE2 antibody, MCH3 antibody, Caspase-7 antibody, MCH3/SCA-2 antibody, SCA-2 antibody, caspase 7 antibody, caspase-7 antibody, caspase 7 S homeolog antibody, CASP7 antibody, xcaspase-7 antibody, casp7 antibody, casp7.S antibody, Casp7 antibody
- UniProt
- P55210
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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