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CAPNL1 抗体

The 小鼠 单克隆 anti-CAPNL1 antibody (Clone 15C10) (ABIN306693) specifically detects CAPNL1 in WB, IP 和 EIA. The antibody is reactive with 人, 小鼠, 大鼠 和 Cow samples.
产品编号 ABIN306693
发货至: 中国
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Quick Overview for CAPNL1 抗体 (ABIN306693)

抗原

See all CAPNL1 抗体
CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

适用

  • 56
  • 22
  • 21
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow

宿主

  • 51
  • 16
  • 1
小鼠

克隆类型

  • 52
  • 16
单克隆

标记

  • 48
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 1
This CAPNL1 antibody is un-conjugated

应用范围

  • 46
  • 36
  • 15
  • 15
  • 12
  • 12
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  • 9
  • 2
  • 1
  • 1
  • 1
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Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

克隆位点

15C10
  • 原理

    Mouse anti Human Calpain I (large subunit, p80)

    交叉反应

    Cow, 人, 小鼠, 大鼠

    产品特性

    The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and μ-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kD subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, μ-calpain is active at micromolar (uM) concentrations of Ca ++. In addition to the ubiquitously expressed m- and μcalpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.

    纯化方法

    Protein A/G Chromatography

    亚型

    IgG1
  • 应用备注

    Use at 0.5-1 μg/mL for ELISA and Western blot, 1-2 μg/mL for immunoprecipitation.

    限制

    仅限研究用
  • 储存条件

    -20 °C

    储存方法

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原

    CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

    背景

    Mouse Anti-Calpain I, u-Calpain (Large subunit, p80), Monoclonal Antibody

    UniProt

    P07384

    途径

    Apoptosis
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