EPH Receptor B1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for EPH Receptor B1 抗体 (C-Term) (ABIN306671)
抗原
See all EPH Receptor B1 (EPHB1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 586-984, C-Term
-
原理
- Sheep anti Human ELK rec tyr Kinase (Eph B1 Cy.)
-
交叉反应
- 人
-
产品特性
- The immunogen used for the anti-human ephB1 (Elk receptor) Dcytoplasmic(CY) region was a GST fusion protein ephB1 (Elk receptor) CY corresponding to amino acid sequence 586-984 of the C terminal, cytoplasmic region and having a molecular weight of 116 kDa. EphB1, previously known as Elk (eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. EphB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. EphB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cell-cell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.
-
纯化方法
- Ammonium Sulfate Precipitation
-
免疫原
- A GST fusion protein ephB1 (Elk receptor) - CY corresponding to amino acid sequence 586-984 of the C terminus region and having a molecular weight of 116 kDa
-
亚型
- IgG
-
-
-
-
应用备注
- Applications: 1-10 μg/mL for Western Blotting and 10-20 μg/mL for immunoprecipitation.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- phosphate buffered saline with 0.08 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
-
-
- EPH Receptor B1 (EPHB1)
-
别名
- ELK rec tyr Kinase (Eph B1 Cy)
-
背景
- Eph B1 (ELK receptor) cytoplasmic, Tyrosine-protein kinase receptor EPH-2, Ephrin type B receptor 1, HEK6
-
UniProt
- P54762
-
途径
- RTK signaling
抗原
-