EPH Receptor B1 抗体 (AA 620-1596)
Quick Overview for EPH Receptor B1 抗体 (AA 620-1596) (ABIN306670)
抗原
See all EPH Receptor B1 (EPHB1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 620-1596
-
交叉反应
- 大鼠
-
产品特性
- Eph B1 (ELK receptor) SAM, Tyrosine-protein kinase receptor EPH-2, Ephrin type B receptor 1, HEK6,Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicated during the process of spermiogenesis and in the actin-based stellate morphology of mesangial cells
-
纯化方法
- Ammonium Sulfate Precipitation
-
免疫原
- Sheep were immunized with a recombinant protein corresponding to amino acids 620-1596 of the SSeCKS protein.
-
亚型
- IgG
-
-
-
-
应用备注
- Antibody can be used for Western blot (2-5 μg/mL), immunohistochemistry and immunoprecipitation. Optimal concentration should be evaluated by serial dilutions.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
-
-
- EPH Receptor B1 (EPHB1)
-
别名
- ELK rec tyr Kinase (Eph B1 SAM)
-
途径
- RTK signaling
抗原
-