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Retinoblastoma Protein (Rb) 抗体 (AA 387-928)

Name: Retinoblastoma Protein (Rb) 抗体 (AA 387-928)
SKU: ABIN306637
Availability: OutOfStock

This 小鼠单克隆 antibody specifically detects Retinoblastoma Protein (Rb) in WB 和 IP. It exhibits reactivity toward 人, 小鼠, 大鼠, 小鸡和 Mink.

产品编号 ABIN306637

发货至: 中国

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Quick Overview for Retinoblastoma Protein (Rb) 抗体 (AA 387-928) (ABIN306637)

抗原

See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体

Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

适用

人, 小鼠, 大鼠, 小鸡, Mink

宿主

小鼠

克隆类型

单克隆

标记

This Retinoblastoma Protein (Rb) antibody is un-conjugated

应用范围

Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

XZ91

Discover our top product Rb Protein Primary Antibody

抗原表位
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AA 387-928

原理

Mouse anti Human Rb (Retinoblastoma)

产品特性

The immunogen for the anti-human retinoblastoma (Rb) was a recombinant protein corresponding to amino acids 393 to 572 of the human retinoblastoma sequence. Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.

纯化方法

Protein A/G Chromatography

免疫原

A recombinant protein corresponding to amino acids 387 to 928 of the human retinoblastoma sequence

亚型

IgG1
anti-Retinoblastoma Protein (Rb Protein) (AA 858-886) antibody
Rb Protein 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (AA 586-615) antibody
Rb Protein 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer811) antibody
Rb Protein 适用: 人 IHC, ELISA, IF, DB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer780) antibody
KD Validated Rb Protein 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3375 unconjugated Recombinant Antibody

anti-Retinoblastoma Protein (Rb Protein) (pSer807) antibody
KD Validated Rb Protein 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3245 unconjugated Recombinant Antibody

anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibody
Rb Protein 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 172C1094 unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer788) antibody
Rb Protein 适用: 人 IHC, ELISA, DB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer780) antibody
Rb Protein 适用: 人 IHC, ELISA, DB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer608) antibody
Rb Protein 适用: 人 IHC, ELISA, DB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (AA 251-268) antibody
Rb Protein 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, Pig, Bat, 马 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Applications: Western Blot, Immunofluorescence

限制

仅限研究用
状态

Liquid

缓冲液

phosphate buffered saline with 0.08 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
抗原

Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

别名

Rb (Retinoblastoma)

背景

Retinoblastoma-associated protein, pRb, pp110, p105-Rb

UniProt

P06400

途径

Mitotic G1-G1/S Phases