ErbB2/Her2 抗体
Quick Overview for ErbB2/Her2 抗体 (ABIN306627)
抗原
See all ErbB2/Her2 抗体适用
宿主
克隆类型
标记
应用范围
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亚型
 - IgG
 
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应用备注
 - Antibody can be used for Western blotting (5-10 ug/ml). Positive Control: Breast carcinomas.
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限制
 - 仅限研究用
 
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浓度
 - 1 mg/ml
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储存条件
 - -20 °C
 
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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别名
 - c-ErbB-2
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背景
 - C-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. Synonyms: HER2, neu, p185erbB2, MLN 19, CD340.
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UniProt
 - P04626
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途径
 - RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
 
抗原
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