Nerve Growth Factor 抗体
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- 抗原 See all Nerve Growth Factor (NGF) 抗体
- Nerve Growth Factor (NGF)
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适用
- 人, 小鼠, Cow, Viper
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Nerve Growth Factor antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP)
- 克隆位点
- AS18
- 亚型
- IgG1
- Top Product
- Discover our top product NGF Primary Antibody
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- 应用备注
- Antibody can be used for immunoprecipitation. Positive Control: PC12 cells.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/ml
- 储存条件
- -20 °C
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- 抗原
- Nerve Growth Factor (NGF)
- 别名
- NGF (Nerve Growth Factor) (NGF 产品)
- 别名
- Beta-NGF antibody, HSAN5 antibody, NGFB antibody, Ngfb antibody, ngfb antibody, ns:zft386 antibody, xx:zft386 antibody, zgc:109730 antibody, beta-NGF antibody, hsan5 antibody, beta-ngf antibody, NGF antibody, ngf antibody, nerve growth factor antibody, nerve growth factor b (beta polypeptide) antibody, nerve growth factor S homeolog antibody, NGF antibody, Ngf antibody, ngfb antibody, ngf antibody, ngf.S antibody
- 背景
- Nerve growth factor (NGF) influences the survival and differentiation of a variety of neuronal and nonneuronal cells. The actions of this polypeptide result from binding to specific cell surface receptors which are present as both high and low affinity sites. Although both types of receptor bind NGF only the high affinity form is capable of signal transduction. Cross-linking studies with 125I-NGF have shown that the high affinity receptor of rat PC12 cells forms an Mr 158,000 complex with NGF while the low affinity receptor forms an Mr 100,000 complex. Full length cDNA clones for both the human and rat NGF receptor genes have been produced and sequenced, revealing greater than 90% homology between the two species. Recently, it has been shown that cells which do not normally respond to NGF only express low affinity receptors from transfected NGF genes but cells which normally are NGF-responsive express high affinity receptors from the same NGF sequences. This supports the hypothesis that the high affinity receptors have a unique component in addition to the subunit common to the low affinity receptors. Synonyms: NGF, hNGF, Beta-nerve growth factor, Beta-NGF, NGF, NGFB.
- UniProt
- P01138
- 途径
- Regulation of Cell Size
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