Epstein-Barr Virus Nuclear Antigen-3A (EBNA-3A) 抗体
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Quick Overview for Epstein-Barr Virus Nuclear Antigen-3A (EBNA-3A) 抗体 (ABIN306583)
抗原
See all Epstein-Barr Virus Nuclear Antigen-3A (EBNA-3A) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Sheep anti EBNA 3A
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产品特性
- EBNA-3A is a latent viral nuclear protein expressed in EBV transformed lymphoblastic cell lines. It is also found in some immunoblastic lymphomas in vivo. This viral nuclear protein is essential for EBV mediated transformation of B lymphocytes. The EBNA-3A functions as a transcriptional regulator though the target genes are currently unknown. Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop
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纯化方法
- Ammonium Sulfate Precipitation
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亚型
- IgG
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应用备注
- Western blotting at 0.25-1.00 μg/mL, Dot blotting, ELISA, Immunocytochemistry and Immunohistochemistry on frozen and paraffin embedded tissues. Optimal concentrations must be determined by titration.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Epstein-Barr Virus Nuclear Antigen-3A (EBNA-3A)
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别名
- EBNA 3A
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物质类
- Viral Protein
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背景
- EBNA3A, Epstein Barr Nuclear Antigen 3A
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UniProt
- Q69138
抗原
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