Adenovirus E1A 抗体
This anti-Adenovirus E1A antibody is a 小鼠 单克隆 antibody detecting Adenovirus E1A in . Suitable for 人.
Quick Overview for Adenovirus E1A 抗体 (ABIN306558)
抗原
Adenovirus E1A (HAdV E1A)
(Human Adenovirus E1A (HAdV E1A))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This Adenovirus E1A antibody is un-conjugated
应用范围
请咨询
克隆位点
M73
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亚型
- IgG2a
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限制
- 仅限研究用
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- Adenovirus E1A (HAdV E1A) (Human Adenovirus E1A (HAdV E1A))
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别名
- E1A (adenovirus early region 1)
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物质类
- Viral Protein
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背景
- The immunogen for the anti- 2 E1A was full length recombinant adenovirus 2 E1A protein. The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105. By immunoprecipitation, adenovirus 2E1A recognizes adenovirus 2 and 5 E1A proteins, 3 bands at 30-50kDa, as well as, E1A associated proteins. 293 cells can be used as positive control and HS27 cells as negative control. Synonyms: mouse anti E1A, Adenovirus Early Region 1, .
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UniProt
- P03254
抗原
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